Prediction of the Risk of Myocardial Infarction from Polymorphisms in Candidate Genes

2002646 citationsJournal Articlebronze Open Access

Authors

Yoshiji Yamada · National Institute of Biotechnology

Hideo Izawa · Nagoya University

Sahoko Ichihara · Nagoya University

Fumimaro Takatsu · Anjo Kosei Hospital

Hitoshi Ishihara · Okazaki City Hospital

Haruo Hirayama · Japanese Red Cross Nagoya Daini Hospital

Takahito Sone ·

Abstract

Determination of the genotypes of the connexin 37, plasminogen-activator inhibitor type 1, and stromelysin-1 genes may prove reliable in predicting the genetic risk of myocardial infarction and might thus contribute to the primary prevention of this condition.

Topics & Keywords

Genetic Associations and Epidemiology Cardiovascular, Neuropeptides, and Oxidative Stress Research Renin-Angiotensin System Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 347, Issue 24, pp. 1916-1923

DOI: 10.1056/nejmoa021445

Field-Weighted Citation Impact: 32.99