The clinical research of sufentanyl combined with local anesthetic caudal block on Soave operation of congenital Hirschsprung' disease in children

【Objective】 To study the effects of anesthesia and analgesia of sufentanly combined with local anesthetic caudal block on the soave operation of congenital hirschsprung'disease on children.【Methods】 40 patients were randomly divided into control group(C group: 0.8% lidocaine+0.25% ropivacaine) and sufentanly group(S group: 0.8% lidocaine+0.25% ropivacaine+sufentanyl 0.5μg/kg),all patients accepted single caudal block after tracheal intubation and inhaled isoflurane only at intra-operation.The heart rate,mean artery pressure of two groups were compared before intubation(T0),after caudal block(T1),expanded anus(T2),seperated colon(T3),after extubation 5 min(T4).The mean end-tidal isoflurane concentration,the grade of anus laxity,patients awaking time,scores of analgesia and sedation postoperative were compared between the two groups.【Results】 The patients' heart rate,mean artery pressure were significant lower in S group than that of C group at the T2,T3,T4.The mean end-tidal isoflurane concentration was significant lower and the awaking time was shorter in S group than that of C group.The scores of Ramsay sedation at postoperative 2,4 and 8 h were significant higher and the scores of FLACC analgeisa at all postoperative time points were significant lower in S group than that of C group.There were not statistic difference of incidence of adverse effect including urine retention,skin pruritus,vomit and respiratory depression between two groups.【Conclusion】 Sufentanly combined with local anesthetic caudal block on the soave operation of congenital hirschsprung'disease on children can provide satisfactory anesthesia effect,postoperative analgesia and sedition action.