Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa

2016185 citationsJournal Articlegold Open Access

Authors

Hossam Murad · Atomic Energy Commission of Syria

Mohammad Hawat

Adnan Ekhtiar · Damascus University

Abdulmunim Aljapawe · Damascus University

Assef Abbas · Tishreen University

Hussein Darwish · Atomic Energy Commission of Syria

Oula Sbenati · Atomic Energy Commission of Syria

Abstract

These findings indicated that ASPE induces G1-phase arrest and apoptosis in MDA-MB-231 cells. ASPE may serve as a potential therapeutic agent for breast cancer.

Topics & Keywords

Seaweed-derived Bioactive Compounds Phytochemical and Pharmacological Studies Marine and coastal plant biology

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Cancer Cell International

Volume 16, Issue 1, pp. 39-39

DOI: 10.1186/s12935-016-0315-4

Field-Weighted Citation Impact: 15.33