Head and Neck Cancer

Head and neck cancer was last reviewed in the Journal in 19831. At that time, there was promising new information on a possible role for chemotherapy1,2. During the past decade, chemotherapy has undergone further investigation and important clinical advances have been made in chemoprevention, organ preservation, and the simultaneous use of chemotherapy and radiation. In this review, we shall discuss the diagnosis of and standard therapy for head and neck cancer, as well as the status of recent basic and clinical investigations.EpidemiologyHead and neck cancer, as defined here, includes the common squamous-cell carcinomas of the . . .