Ru-Catalyzed highly site-selective C–H bond arylation of 9-(pyrimidin-2-yl)-9H-carbazole

201621 citationsJournal Article

Authors

K. Harsha Vardhan Reddy · University of Hyderabad

R. Uday Kumar · University of Hyderabad

V. Prakash Reddy · Indian Institute of Chemical Technology

G. Satish · University of Hyderabad

Jagadeesh Babu Nanubolu · Indian Institute of Chemical Technology

Y. V. D. Nageswar · Ministry of Civil Affairs

Abstract

We describe an efficient ruthenium-catalyzed C–H bond <italic>ortho</italic>-arylation of 9-(pyrimidin-2-yl)-9<italic>H</italic>-carbazole using boronic acids. This methodology exhibits excellent and high site-selectivity, functional group tolerance and gave the desired product in moderate to good yields.

Topics & Keywords

Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions Histone Deacetylase Inhibitors Research

Publication Details

Published in: RSC Advances

Volume 6, Issue 59, pp. 54431-54434

DOI: 10.1039/c6ra09825h

Field-Weighted Citation Impact: 1.35

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Ru-Catalyzed highly site-selective C–H bond arylation of 9-(pyrimidin-2-yl)-9H-carbazole

Authors

Abstract

Topics & Keywords

Publication Details