3D Porous Crystalline Polyimide Covalent Organic Frameworks for Drug Delivery

20151,041 citationsJournal Article

Authors

Qianrong Fang · Jilin University

Junhua Wang · University of Delaware

Shuang Gu · University of Delaware

Robert B. Kaspar · University of Delaware

Zhongbin Zhuang · University of Delaware

Jie Zheng · University of Delaware

Hongxia Guo ·

Abstract

Three-dimensional porous crystalline polyimide covalent organic frameworks (termed PI-COFs) have been synthesized. These PI-COFs feature non- or interpenetrated structures that can be obtained by choosing tetrahedral building units of different sizes. Both PI-COFs show high thermal stability (>450 °C) and surface area (up to 2403 m(2) g(-1)). They also show high loading and good release control for drug delivery applications.

Topics & Keywords

Covalent Organic Framework Applications Metal-Organic Frameworks: Synthesis and Applications Luminescence and Fluorescent Materials

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of the American Chemical Society

Volume 137, Issue 26, pp. 8352-8355

DOI: 10.1021/jacs.5b04147

Field-Weighted Citation Impact: 30.82