Storage of Platelet Concentrates at 22°C

Abstract A technique has been proposed which allows easy preparation of platelet concentrates within a closed, sterile system and maximal utilization of other blood components. Lifespan studies have been performed to demonstrate the viability of platelets prepared in this manner. Such concentrates can be stored for as long as three days with adequate maintenance of viability for tranfusion purposes if certain technical requirements are met. Important among these are attention to concentrate volume and pH; agitation of the concentrate is helpful for maintenance of viability. Twelve studies in thrombocytopenic recipients suggest that stored concentrates will be safe and effective in transfusion practice.