Plasma <i>ESR1</i> Mutations and the Treatment of Estrogen Receptor–Positive Advanced Breast Cancer

2016703 citationsJournal Article

Authors

Charlotte Fribbens · Institute of Cancer Research

Ben O’Leary · Institute of Cancer Research

Lucy Kilburn · Institute of Cancer Research

Sarah Hrebien · Institute of Cancer Research

Isaac García-Murillas · Institute of Cancer Research

Matthew Beaney · Institute of Cancer Research

Massimo Cristofanilli

Abstract

ESR1 mutation analysis in plasma after progression after prior AI therapy may help direct choice of further endocrine-based therapy. Additional confirmatory studies are required.

Topics & Keywords

Advanced Breast Cancer Therapies Lung Cancer Research Studies Breast Cancer Treatment Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 34, Issue 25, pp. 2961-2968

DOI: 10.1200/jco.2016.67.3061

Field-Weighted Citation Impact: 71.75