Genomic Classification and Prognosis in Acute Myeloid Leukemia

20164,284 citationsJournal Articlebronze Open Access

Authors

Elli Papaemmanuil · Bioinformatics Institute

Moritz Gerstung · Wellcome Sanger Institute

Lars Bullinger · Bioinformatics Institute

Verena I. Gaidzik · European Bioinformatics Institute

Peter Paschka · European Bioinformatics Institute

Nicola D. Roberts · European Bioinformatics Institute

Nicola Potter

Abstract

The driver landscape in AML reveals distinct molecular subgroups that reflect discrete paths in the evolution of AML, informing disease classification and prognostic stratification. (Funded by the Wellcome Trust and others; ClinicalTrials.gov number, NCT00146120.).

Topics & Keywords

Acute Myeloid Leukemia Research Myeloproliferative Neoplasms: Diagnosis and Treatment Cancer Genomics and Diagnostics

UN Sustainable Development Goals

No poverty

Publication Details

Published in: New England Journal of Medicine

Volume 374, Issue 23, pp. 2209-2221

DOI: 10.1056/nejmoa1516192

Field-Weighted Citation Impact: 239.82