Pretreatment blood–brain barrier disruption and post-endovascular intracranial hemorrhage

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Authors

Richard Leigh · National Institutes of Health

Sören Christensen · National Institutes of Health

Bruce Campbell · National Institutes of Health

Michael P. Marks · National Institutes of Health

Gregory W. Albers · National Institutes of Health

Maarten G. Lansberg · National Institutes of Health

For the DEFUSE 2 Investigators

Abstract

The amount of BBB disruption on pretreatment MRI is associated with the severity of ICH after acute intervention. This relationship has now been identified in patients receiving IV, endovascular, and combined therapies. Further study is needed to determine its role in guiding treatment.

Topics & Keywords

Acute Ischemic Stroke Management Intracerebral and Subarachnoid Hemorrhage Research Traumatic Brain Injury and Neurovascular Disturbances

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 87, Issue 3, pp. 263-269

DOI: 10.1212/wnl.0000000000002862

Field-Weighted Citation Impact: 4.53