Effect of spironolactone on patients with resistant hypertension and obstructive sleep apnea

201695 citationsJournal Article

Authors

Lirui Yang · Chinese Academy of Medical Sciences & Peking Union Medical College

Huimin Zhang · Chinese Academy of Medical Sciences & Peking Union Medical College

Menggengtuya Cai · Xinjiang Uygur Autonomous Region Disease Prevention and Control Center

Yubao Zou · Chinese Academy of Medical Sciences & Peking Union Medical College

Xiongjing Jiang · Chinese Academy of Medical Sciences & Peking Union Medical College

Lei Song · Chinese Academy of Medical Sciences & Peking Union Medical College

Abstract

Spironolactone reduced the severity of OSA and reduced blood pressure in resistant hypertension patients with moderate-to-severe OSA. These findings may assist in the treatment of OSA in patients with resistant hypertension.

Topics & Keywords

Hormonal Regulation and Hypertension Cardiovascular, Neuropeptides, and Oxidative Stress Research Obstructive Sleep Apnea Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical and Experimental Hypertension

Volume 38, Issue 5, pp. 464-468

DOI: 10.3109/10641963.2015.1131290

Field-Weighted Citation Impact: 7.57