Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

2016426 citationsJournal Articlebronze Open Access

Authors

Paul K. Crane · University of Washington

Laura E. Gibbons · University of Washington

Kristen Dams-O’Connor

Emily H. Trittschuh · University of Washington

James B. Leverenz · Cleveland Clinic

C. Dirk Keene · University of Washington

Joshua A. Sonnen · University of Utah

Abstract

Pooled clinical and neuropathologic data from 3 prospective cohort studies indicate that TBI with LOC is associated with risk for Lewy body accumulation, progression of parkinsonism, and PD, but not dementia, AD, neuritic plaques, or neurofibrillary tangles.

Topics & Keywords

Traumatic Brain Injury Research Traumatic Brain Injury and Neurovascular Disturbances Dementia and Cognitive Impairment Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Neurology

Volume 73, Issue 9, pp. 1062-1062

DOI: 10.1001/jamaneurol.2016.1948

Field-Weighted Citation Impact: 32.41