DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy

2016109 citationsJournal Articlediamond Open Access

Authors

Sarah E. Reese

Shanshan Zhao · National Institutes of Health

Michael C. Wu · Fred Hutch Cancer Center

Bonnie R. Joubert · Triangle

Christine L Parr · Centre for Chronic Disease Control

Siri E. Håberg · Norwegian Institute of Public Health

Per Magne Ueland · Haukeland University Hospital

Abstract

Our smoking methylation score represents a promising novel biomarker of sustained maternal smoking during pregnancy easily calculated with Illumina450K or IlluminaEPIC data. It may help identify novel health impacts and improve adjustment for smoking when studying other risk factors with more subtle effects.

Topics & Keywords

Epigenetics and DNA Methylation Smoking Behavior and Cessation Cancer Risks and Factors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Environmental Health Perspectives

Volume 125, Issue 4, pp. 760-766

DOI: 10.1289/ehp333

Field-Weighted Citation Impact: 7.63