Functionalization of pyridyl ketones using deprotolithiation-in situ zincation

201627 citationsJournal Articlegreen Open Access

Authors

Madani Hedidi · Centre National de la Recherche Scientifique

William Erb · Université de Rennes

Frédéric Lassagne · Centre National de la Recherche Scientifique

Yury S. Halauko · Minsk Institute of Management

Олег А. Ивашкевич · Minsk Institute of Management

Вадим Э. Матулис · Belarusian State University

Thierry Roisnel

Abstract

Metallation of aryl ketones was achieved by using LiTMP in the presence of ZnCl<sub>2</sub>·TMEDA, as evidenced by subsequent interception with iodine or by palladium-catalysed cross-coupling reaction.

Topics & Keywords

Coordination Chemistry and Organometallics Catalytic Cross-Coupling Reactions Catalytic C–H Functionalization Methods

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: RSC Advances

Volume 6, Issue 68, pp. 63185-63189

DOI: 10.1039/c6ra11370b

Field-Weighted Citation Impact: 2.97