Preoperative HE4, CA125 and ROMA in the differential diagnosis of benign and malignant adnexal masses

201649 citationsJournal Articlegold Open Access

Authors

Katarzyna M. Terlikowska · Medical University of Białystok

Bożena Dobrzycka · Medical University of Białystok

Anna Maria Witkowska · Medical University of Białystok

Beata Maćkowiak-Matejczyk

Tomasz Kamil Sledziewski · Medical University of Białystok

Maciej Kinalski · Wojewódzki Szpital Zespolony im. Jędrzeja Śniadeckiego

S Terlikowski · Medical University of Białystok

Abstract

The ROMA algorithm shows the best diagnostic performance to distinguish epithelial ovarian cancer from benign ovarian disease. We found the high specificity of HE4 and CA125 while differentiating ovarian benign diseases from epithelial ovarian cancer in postmenopausal women and the high sensitivity of CA125 in detecting epithelial ovarian cancer in premenopausal patients.

Topics & Keywords

Ovarian cancer diagnosis and treatment Intraperitoneal and Appendiceal Malignancies Endometrial and Cervical Cancer Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Ovarian Research

Volume 9, Issue 1, pp. 43-43

DOI: 10.1186/s13048-016-0254-7

Field-Weighted Citation Impact: 8.79