Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes

2016314 citationsJournal Articlehybrid Open Access

Authors

Jon White · University College London

Daniel I. Swerdlow · Farr Institute

David Preiss · University of Oxford

Zammy Fairhurst-Hunter · Centre for Human Genetics

Brendan J. Keating · Children's Hospital of Philadelphia

Folkert W. Asselbergs · University Medical Center Utrecht

Naveed Sattar

Abstract

Routinely measured lipid fractions exhibit contrasting associations with the risk of CAD and diabetes. Increased LDL-C, HDL-C, and possibly TG levels are associated with a lower risk of diabetes. This information will be relevant to the design of clinical trials of lipid-modifying agents, which should carefully monitor participants for dysglycemia and the incidence of diabetes.

Topics & Keywords

Genetic Associations and Epidemiology Lipoproteins and Cardiovascular Health Diabetes, Cardiovascular Risks, and Lipoproteins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Cardiology

Volume 1, Issue 6, pp. 692-692

DOI: 10.1001/jamacardio.2016.1884

Field-Weighted Citation Impact: 32.43