Barriers to drug adherence in the treatment of urea cycle disorders: Assessment of patient, caregiver and provider perspectives

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Authors

Oleg A. Shchelochkov · University of Iowa Hospitals and Clinics

Klara Dickinson · Anthera Pharmaceuticals (United States)

Bruce F. Scharschmidt · Horizon Therapeutics (United States)

Brendan Lee · Baylor College of Medicine

Miguel Marino · Oregon Health & Science University

Cynthia Le Mons · National Urea Cycle Disorders Foundation

Abstract

Despite positive views of their effectiveness, respondents found medications, medical foods and dietary supplements difficult to take and viewed adherence as inadequate, thus contributing to hyperammonemic episodes.

Topics & Keywords

Metabolism and Genetic Disorders Bipolar Disorder and Treatment Amino Acid Enzymes and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Genetics and Metabolism Reports

Volume 8, pp. 43-47

DOI: 10.1016/j.ymgmr.2016.07.003

Field-Weighted Citation Impact: 2.60