An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

2016776 citationsJournal Articlegold Open Access

Authors

Steve Horvath · University of California, Los Angeles

Michael Gurven · University of California, Santa Barbara

Morgan E. Levine · University of California, Los Angeles

Benjamin C. Trumble · University of California, Santa Barbara

Hillard Kaplan · University of New Mexico

Hooman Allayee · University of Southern California

Beate Ritz

Abstract

Epigenetic aging rates are significantly associated with sex, race/ethnicity, and to a lesser extent with CHD risk factors, but not with incident CHD outcomes. These results may help elucidate lower than expected mortality rates observed in Hispanics, older African-Americans, and women.

Topics & Keywords

Epigenetics and DNA Methylation Birth, Development, and Health Intergenerational Family Dynamics and Caregiving

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genome biology

Volume 17, Issue 1, pp. 171-171

DOI: 10.1186/s13059-016-1030-0

Field-Weighted Citation Impact: 35.33