Botulinum Toxin A: Dose-dependent Effect on Reepithelialization and Angiogenesis

201630 citationsJournal Articlegold Open Access

Authors

Alfred Gugerell · Medical University of Graz

Johanna Kober · Medical University of Graz

Melanie Schmid · Medical University of Graz

Elisabeth Buchberger · Medical University of Graz

Lars‐Peter Kamolz · Medical University of Graz

Maike Keck · Medical University of Graz

Abstract

High concentrations of botulinum toxin interfered with wound closure as keratinocytes' proliferation and migration were deteriorated. Furthermore, BoNT concentrations of 20 IU/mL constrain in vitro vessel formation but do not influence proliferation or migration of endothelial cells.

Topics & Keywords

Botulinum Toxin and Related Neurological Disorders Sympathectomy and Hyperhidrosis Treatments Dermatologic Treatments and Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Plastic & Reconstructive Surgery Global Open

Volume 4, Issue 8, pp. e837-e837

DOI: 10.1097/gox.0000000000000852

Field-Weighted Citation Impact: 0.90