Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension

20161,218 citationsJournal Articlebronze Open Access

Authors

Peter J. Hutchinson · Leeds General Infirmary

Angelos G. Kolias · Leeds General Infirmary

Ivan Timofeev · Leeds General Infirmary

Elizabeth A. Corteen · Leeds General Infirmary

Marek Czosnyka · Leeds General Infirmary

Jake Timothy · Addenbrooke's Hospital

Ian Anderson ·

Abstract

At 6 months, decompressive craniectomy in patients with traumatic brain injury and refractory intracranial hypertension resulted in lower mortality and higher rates of vegetative state, lower severe disability, and upper severe disability than medical care. The rates of moderate disability and good recovery were similar in the two groups. (Funded by the Medical Research Council and others; RESCUEicp Current Controlled Trials number, ISRCTN66202560 .).

Topics & Keywords

Traumatic Brain Injury and Neurovascular Disturbances Neurosurgical Procedures and Complications S100 Proteins and Annexins

Publication Details

Published in: New England Journal of Medicine

Volume 375, Issue 12, pp. 1119-1130

DOI: 10.1056/nejmoa1605215

Field-Weighted Citation Impact: 83.55

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Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension

Authors

Abstract

Topics & Keywords

Publication Details