Isoliquiritigenin and liquiritin from Glycyrrhiza uralensis inhibit α-synuclein amyloid formation

201619 citationsJournal Article

Authors

Mingyan Liao · Huazhong University of Science and Technology

Biao Cheng · American Association of Colleges of Pharmacy

Kun Huang · Wuhan Institute of Bioengineering

Abstract

Bioactive isoliquiritigenin and liquiritin inhibit α-synuclein aggregation and extend the life span of the<italic>C. elegans</italic>model of Parkinson's disease.

Topics & Keywords

Pharmacological Effects of Natural Compounds Ginseng Biological Effects and Applications Tryptophan and brain disorders

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: RSC Advances

Volume 6, Issue 89, pp. 86640-86649

DOI: 10.1039/c6ra17770k

Field-Weighted Citation Impact: 3.27