Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

Back to research

Metformin attenuates lung fibrosis development via NOX4 suppression

2016226 citationsJournal Articlegold Open Access

Authors

Nahoko Sato · Jikei University School of Medicine

Naoki Takasaka · State Key Laboratory of Respiratory Disease

Masahiro Yoshida · Jikei University School of Medicine

Kazuya Tsubouchi · State Key Laboratory of Respiratory Disease

Shunsuke Minagawa · State Key Laboratory of Respiratory Disease

Jun Araya · State Key Laboratory of Respiratory Disease

Abstract

These findings suggest that metformin can be a promising anti-fibrotic modality of treatment for IPF affected by TGF-β.

Topics & Keywords

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Oral and gingival health research Cancer Diagnosis and Treatment

Publication Details

Published in: Respiratory Research

Volume 17, Issue 1, pp. 107-107

DOI: 10.1186/s12931-016-0420-x

Field-Weighted Citation Impact: 16.91

Metformin attenuates lung fibrosis development via NOX4 suppression | Researchclopedia

· Jikei University School of Medicine

Yu Fujita · State Key Laboratory of Respiratory Disease

Yusuke Kurita · Jikei University School of Medicine

Kenji Kobayashi · Jikei University School of Medicine

Saburo Ito · State Key Laboratory of Respiratory Disease

Hiromichi Hara · State Key Laboratory of Respiratory Disease

Tsukasa Kadota · State Key Laboratory of Respiratory Disease

Haruhiko Yanagisawa · State Key Laboratory of Respiratory Disease

Mitsuo Hashimoto · Jikei University School of Medicine

Hirofumi Utsumi · State Key Laboratory of Respiratory Disease

Hiroshi Wakui · Jikei University School of Medicine

Jun Kojima · State Key Laboratory of Respiratory Disease

Takanori Numata · Jikei University School of Medicine

Yumi Kaneko · State Key Laboratory of Respiratory Disease

Makoto Odaka · Chest Diseases Hospital

Toshiaki Morikawa · Jikei University School of Medicine

Katsutoshi Nakayama · State Key Laboratory of Respiratory Disease

Hirotsugu Kohrogi · Kumamoto University

Kazuyoshi Kuwano · Jikei University School of Medicine