Probiotic and synbiotic therapy in critical illness: a systematic review and meta-analysis

2016290 citationsReviewgold Open Access

Authors

William Manzanares · Universidad de la República

Margot Lemieux · Clinical Evaluation Research Unit

Pascal L. Langlois · Université de Sherbrooke

Paul E. Wischmeyer · University of Colorado Denver

Abstract

Probiotics show promise in reducing infections, including VAP in critical illness. Currently, clinical heterogeneity and potential publication bias reduce strong clinical recommendations and indicate further high quality clinical trials are needed to conclusively prove these benefits.

Topics & Keywords

Nosocomial Infections in ICU Gut microbiota and health Probiotics and Fermented Foods

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care

Volume 20, Issue 1, pp. 262-262

DOI: 10.1186/s13054-016-1434-y

Field-Weighted Citation Impact: 22.19