NAD+-CONVERTING ENZYMES IN NEURONAL AND GLIAL CELLS: CD38 AS A NOVEL TARGET FOR NEUROPROTECTION

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Authors

А. Б. Салмина · Krasnoyarsk State Medical University

А. И. Инжутова · Krasnoyarsk State Medical University

А. В. Моргун · Krasnoyarsk State Medical University

О. С. Окунева · Krasnoyarsk State Medical University

N. A. Malinovskaya · Krasnoyarsk State Medical University

Olga L. Lopatina · Krasnoyarsk State Medical University

М. М. Петрова

Abstract

The review contains current data on molecular mechanisms which control NAD+ homeostasis in brain cells. It also deals with the role of NAD+-converting enzymes in regulation of functional activity, viability and intercellular communication of neuronal and glial cells. Special attention is paid to involvement of CD38 into regulation of NAD+ levels in brain cells in normal and pathological conditions.

Topics & Keywords

Calcium signaling and nucleotide metabolism Molecular Sensors and Ion Detection Receptor Mechanisms and Signaling

Publication Details

Published in: Annals of the Russian academy of medical sciences

Volume 67, Issue 10, pp. 29-37

DOI: 10.15690/vramn.v67i10.413

Field-Weighted Citation Impact: 1.86

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NAD+-CONVERTING ENZYMES IN NEURONAL AND GLIAL CELLS: CD38 AS A NOVEL TARGET FOR NEUROPROTECTION

Authors

Abstract

Topics & Keywords

Publication Details