Stratification of unresponsive patients by an independently validated index of brain complexity

2016486 citationsJournal Articlehybrid Open Access

Authors

Silvia Casarotto · University of Milan

Angela Comanducci · University of Milan

Mario Rosanova · University of Milan

Simone Sarasso · University of Milan

Matteo Fecchio · University of Milan

Martino Napolitani · University of Milano-Bicocca

Andrea Pigorini ·

Abstract

Given its high sensitivity and specificity in the benchmark and MCS population, PCI offers a reliable, independently validated stratification of unresponsive patients that has important physiopathological and therapeutic implications. In particular, the high-PCI subgroup of VS patients may retain a capacity for consciousness that is not expressed in behavior. Ann Neurol 2016;80:718-729.

Topics & Keywords

Traumatic Brain Injury Research Traumatic Brain Injury and Neurovascular Disturbances Functional Brain Connectivity Studies

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Annals of Neurology

Volume 80, Issue 5, pp. 718-729

DOI: 10.1002/ana.24779

Field-Weighted Citation Impact: 26.72