OnabotulinumtoxinA vs Sacral Neuromodulation on Refractory Urgency Urinary Incontinence in Women

2016219 citationsJournal Articlegreen Open Access

Authors

Cindy L. Amundsen · Duke University

Holly E. Richter · University of Alabama at Birmingham

Shawn A. Menefee · Kaiser Permanente San Diego Medical Center

Yuko M. Komesu · University of New Mexico

Lily A. Arya · University of Pennsylvania

W. Thomas Gregory · Oregon Health & Science University

Deborah L. Myers

Abstract

Among women with refractory urgency urinary incontinence, treatment with onabotulinumtoxinA compared with sacral neuromodulation resulted in a small daily improvement in episodes that although statistically significant is of uncertain clinical importance. In addition, it resulted in a higher risk of urinary tract infections and need for transient self-catheterizations.

Topics & Keywords

Pelvic floor disorders treatments Urinary Bladder and Prostate Research Urinary Tract Infections Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 316, Issue 13, pp. 1366-1366

DOI: 10.1001/jama.2016.14617

Field-Weighted Citation Impact: 23.08