Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

20161,595 citationsJournal Articlegold Open Access

Authors

Ruth Pidsley · Garvan Institute of Medical Research

Elena Zotenko · Garvan Institute of Medical Research

Timothy J. Peters · Garvan Institute of Medical Research

Mitchell G. Lawrence · Monash University

Gail P. Risbridger · Monash University

Peter L. Molloy · CSIRO Health and Biosecurity

Susan Van Djik

Abstract

The EPIC array is a significant improvement over the HM450 array, with increased genome coverage of regulatory regions and high reproducibility and reliability, providing a valuable tool for high-throughput human methylome analyses from diverse clinical samples.

Topics & Keywords

Epigenetics and DNA Methylation Genomics and Chromatin Dynamics RNA modifications and cancer

Publication Details

Published in: Genome biology

Volume 17, Issue 1, pp. 208-208

DOI: 10.1186/s13059-016-1066-1

Field-Weighted Citation Impact: 38.89

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Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

Authors

Abstract

Topics & Keywords

Publication Details