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Soil salinity is a global issue threatening land productivity, and estimates predict that 50% of all arable land will become impacted by salinity by 2050. Consequently, it is important to have a fundamental understanding of crop response to salinity to minimize economic loss and improve food security. While an immense amount of research has been performed assessing corn ( Zea mays L.) and soybean [ Glycine max (L.) Merr.] response to salinity, there are few, if any, comprehensive reviews compiling previously published literature. This review provides a detailed description of our current knowledge on the impacts of salinity on corn and soybean growth and development. Both osmotic stress and specific ion toxicities with respect to corn and soybean are addressed. Additionally, potential areas of future research are recommended. Core Ideas Review of salinity's effects on corn and soybean growth and development. Impacts of osmotic stress and specific ion toxicities discussed. Potential areas of future research addressed.