Surgical Management of Endo-Perio Lesion with Demineralised Bone Matrix in Combination with Platelet Rich Fibrin: A Case Report

Periodontal disease is a chronic inflammatory disease process that eventually leads to loss of periodontal attachment and an eventual, bone destruction. The objective of periodontal therapy is to regenerate the lost periodontal tissues. Platelets are rich in growth factors that may contribute to an accelerated process of tissue regeneration. Demineralised bone matrix, (DMBM) xenograft is a bone inductive, sterile, bioresorbable, graft composed of Type I collagen. Given the unique properties of autologous platelet rich fibrin (PRF) and already demonstrated regenerative capacity of commercially available bone grafts, application of a combination approach was attempted. We herewith present a case report of a combined endo-perio lesion that was treated by a combination of autologous PRF and bovine derived xenograft, assessed clinically and radiographically.