Intramyocardial Stem Cell Injection in Patients With Ischemic Cardiomyopathy

2011317 citationsJournal Articlebronze Open Access

Authors

Adam Williams · BioCardia (United States)

Barry Trachtenberg · BioCardia (United States)

Darcy L. Velazquez · University of Miami

Ian McNiece · BioCardia (United States)

Peter Altman · BioCardia (United States)

Didier Rouy · University of Miami

Adam Mendizabal ·

Abstract

These data suggest that transcatheter, intramyocardial injections of autologous bone marrow progenitor cells improve regional contractility of a chronic myocardial scar, and these changes predict subsequent reverse remodeling. The findings support the potential clinical benefits of this new treatment strategy and ongoing randomized clinical trials.

Topics & Keywords

Cardiovascular Function and Risk Factors Cardiac Structural Anomalies and Repair Mesenchymal stem cell research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Research

Volume 108, Issue 7, pp. 792-796

DOI: 10.1161/circresaha.111.242610

Field-Weighted Citation Impact: 30.56