Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

Back to research

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

2016353 citationsJournal Articlebronze Open Access

Authors

Filippos Kottakis · Massachusetts General Hospital

Brandon Nicolay · Harvard University

Ahlima Roumane · Massachusetts General Hospital

Rahul Karnik · Harvard University

Hongcang Gu · Harvard University

Julia M. Nagle · Massachusetts General Hospital

Myriam Boukhali ·

Topics & Keywords

Epigenetics and DNA Methylation Metabolism, Diabetes, and Cancer Cancer, Hypoxia, and Metabolism

Publication Details

Published in: Nature

Volume 539, Issue 7629, pp. 390-395

DOI: 10.1038/nature20132

Field-Weighted Citation Impact: 17.23

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis | Researchclopedia

Massachusetts General Hospital

Michele C. Hayward · UNC Lineberger Comprehensive Cancer Center

Yvonne Y. Li · Brigham and Women's Hospital

Ting Chen · Brigham and Women's Hospital

Marc Liesa · Boston University

Peter S. Hammerman · Brigham and Women's Hospital

Kwok‐Kin Wong · Harvard University

D. Neil Hayes · UNC Lineberger Comprehensive Cancer Center

Orian S. Shirihai · Boston University

Nicholas J. Dyson · Harvard University

Wilhelm Haas · Harvard University

Alexander Meissner · Harvard University

Nabeel Bardeesy · Massachusetts General Hospital