Randomized Comparison of Allogeneic Versus Autologous Mesenchymal Stem Cells for Nonischemic Dilated Cardiomyopathy

2016345 citationsJournal Articlehybrid Open Access

Authors

Joshua M. Hare · University of Miami

Darcy L. DiFede · University of Miami

Angela C. Rieger · University of Miami

Victoria Florea · University of Miami

Ana Marie Landin · University of Miami

Jill El-Khorazaty · Emmes (United States)

Aisha Khan ·

Abstract

These findings demonstrated safety and clinically meaningful efficacy of allo-hMSC versus auto-hMSC in NIDCM patients. Pivotal trials of allo-hMSCs are warranted based on these results. (Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis in Dilated Cardiomyopathy [PoseidonDCM]; NCT01392625).

Topics & Keywords

Cardiac Structural Anomalies and Repair Cardiac Fibrosis and Remodeling Tissue Engineering and Regenerative Medicine

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of the American College of Cardiology

Volume 69, Issue 5, pp. 526-537

DOI: 10.1016/j.jacc.2016.11.009

Field-Weighted Citation Impact: 39.59