Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

201670 citationsJournal Articlegold Open Access

Authors

EMBRACE · Dana-Farber Cancer Institute

Timothy R. Rebbeck · Dana-Farber Cancer Institute

HEBON · University of Pennsylvania

Tara M. Friebel · Kaiser Permanente Washington Health Research Institute

Nandita Mitra · University of Southern California

Fei Wan · Mount Sinai Hospital

Stephanie Chen · University of Southern California

Abstract

Our observations suggest that clinical TH phenotypes resemble SH1. However, TH breast tumor marker characteristics are phenotypically intermediate to SH1 and SH2.

Topics & Keywords

BRCA gene mutations in cancer Ovarian cancer diagnosis and treatment Genomic variations and chromosomal abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Breast Cancer Research

Volume 18, Issue 1, pp. 112-112

DOI: 10.1186/s13058-016-0768-3

Field-Weighted Citation Impact: 4.51