A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials

201654 citationsJournal Articlehybrid Open Access

Authors

Lawrence S. Gazda · The Rogosin Institute

James E. Collins · University of Minnesota

Archie Lovatt · Nippon Sheet Glass (United Kingdom)

Robert W. Holdcraft · The Rogosin Institute

Merribeth J. Morin · BioStrategies (United States)

Daniel Galbraith · Sartorius (United Kingdom)

Melanie L. Graham

Abstract

The four-checkpoint program is a robust and reliable method for characterization of the microbiological safety of encapsulated porcine islets intended for clinical trials.

Topics & Keywords

Pancreatic function and diabetes Xenotransplantation and immune response Diabetes and associated disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Xenotransplantation

Volume 23, Issue 6, pp. 444-463

DOI: 10.1111/xen.12277

Field-Weighted Citation Impact: 7.97