Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

2016221 citationsReviewgreen Open Access

Authors

Gregory T. Jones · St. Gregory's University

Gerard Tromp · Apple (Israel)

Helena Kuivaniemi · TiGenix (Spain)

Sólveig Grétarsdóttir · Council for Scientific and Industrial Research

Annette F. Baas · The Aerospace Corporation

Betti Giusti · TiGenix (Spain)

Ewa Strauss ·

Abstract

The 4 new risk loci for AAA seem to be specific for AAA compared with other cardiovascular diseases and related traits suggesting that traditional cardiovascular risk factor management may only have limited value in preventing the progression of aneurysmal disease.

Topics & Keywords

Aortic aneurysm repair treatments Aortic Disease and Treatment Approaches Connective tissue disorders research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Research

Volume 120, Issue 2, pp. 341-353

DOI: 10.1161/circresaha.116.308765

Field-Weighted Citation Impact: 16.18