Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease

2016194 citationsReviewhybrid Open Access

Authors

Fan Liao · Washington University in St. Louis

Abstract

Emerging data suggest that ApoE affects several amyloid β-independent pathways. These underexplored pathways may provide new insights into Alzheimer's disease pathogenesis. However, it will be important to determine to what extent each mechanism contributes to the pathogenesis of Alzheimer's disease.

Topics & Keywords

Alzheimer's disease research and treatments Cholesterol and Lipid Metabolism Nuclear Receptors and Signaling

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Current Opinion in Lipidology

Volume 28, Issue 1, pp. 60-67

DOI: 10.1097/mol.0000000000000383

Field-Weighted Citation Impact: 7.40