Antibiotics-induced depletion of mice microbiota induces changes in host serotonin biosynthesis and intestinal motility

2017273 citationsJournal Articlegold Open Access

Authors

Xiaolong Ge · Nanjing General Hospital of Nanjing Military Command

Chao Ding · Nanjing General Hospital of Nanjing Military Command

Wei Zhao · Model Animal Research Center

Lizhi Xu · Nanjing Medical University

Hongliang Tian · Nanjing General Hospital of Nanjing Military Command

Jianfeng Gong · Nanjing General Hospital of Nanjing Military Command

Min‐Sheng Zhu

Abstract

Gut microbiota play an important role in the regulation of intestinal bile acids and serotonin metabolism, which could probably contribute to the association between gut microbiota and gastrointestinal motility as intermediates.

Topics & Keywords

Gastrointestinal motility and disorders Gut microbiota and health Diet and metabolism studies

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Journal of Translational Medicine

Volume 15, Issue 1, pp. 13-13

DOI: 10.1186/s12967-016-1105-4

Field-Weighted Citation Impact: 14.05