Iodinated cyanine dyes: a new class of sensitisers for use in NIR activated photodynamic therapy (PDT)

2017187 citationsJournal Articlegreen Open Access

Authors

Jordan Atchison · Biomedical Research Institute

Sukanta Kamila · Biomedical Research Institute

Heather Nesbitt · Biomedical Research Institute

Kieran A. Logan · University of Ulster

Dean Nicholas · University of Ulster

Colin Fowley · Biomedical Research Institute

James Davis ·

Abstract

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in two pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

Topics & Keywords

Nanoplatforms for cancer theranostics Photodynamic Therapy Research Studies Luminescence and Fluorescent Materials

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Chemical Communications

Volume 53, Issue 12, pp. 2009-2012

DOI: 10.1039/c6cc09624g

Field-Weighted Citation Impact: 7.58