Pharmacokinetics and pharmacodynamics of single doses of rivaroxaban in obese patients prior to and after bariatric surgery

201762 citationsJournal Articlebronze Open Access

Authors

Dino Kröll · University Hospital of Bern

Guido Stirnimann · University Hospital of Bern

Andreas Vogt · University Hospital of Bern

Desirée Lin Lee Lai · University of Bern

Yves Borbély · University of Bern

Julia Altmeier · University of Bern

Sabine Schädelin ·

Abstract

Bariatric surgery does not appear to alter PK of rivaroxaban in a clinically relevant way. Effective prophylactic postbariatric anticoagulation is supported by changes in PD.

Topics & Keywords

Venous Thromboembolism Diagnosis and Management Atrial Fibrillation Management and Outcomes Antiplatelet Therapy and Cardiovascular Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Clinical Pharmacology

Volume 83, Issue 7, pp. 1466-1475

DOI: 10.1111/bcp.13243

Field-Weighted Citation Impact: 5.53