Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies

20171,383 citationsReviewgreen Open Access

Authors

Cristiano A. Köhler · Universidade Federal do Ceará

Thiago Holanda Freitas · Universidade Federal do Ceará

Michaël Maes · Universidade Estadual de Londrina

Nayanna Quezado de Andrade · Universidade Federal do Ceará

C. S. Liu · Sunnybrook Health Science Centre

Brisa S. Fernandes · Universidade Federal do Rio Grande do Sul

Brendon Stubbs

Abstract

Our results further characterize a cytokine/chemokine profile associated with MDD. Future studies are warranted to further elucidate sources of heterogeneity, as well as biosignature cytokines secreted by other immune cells.

Topics & Keywords

Tryptophan and brain disorders Stress Responses and Cortisol Health, psychology, and well-being

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Acta Psychiatrica Scandinavica

Volume 135, Issue 5, pp. 373-387

DOI: 10.1111/acps.12698

Field-Weighted Citation Impact: 35.58