Efficacy and Safety of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia

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Authors

Mariko Harada‐Shiba · Cardiovascular Research Center

Katsunori Ikewaki · National Defense Medical College

Atsushi Nohara · Kanazawa University

Yoshihiko Otsubo · Koga Hospital

Koji Yanagi · Osaka Hospital

Masayuki Yoshida · Tokyo Medical and Dental University

Qing Chang ·

Abstract

Lomitapide, added to ongoing treatment with other LLTs, was effective in rapidly and significantly reducing the levels of LDL-C and other atherogenic apolipoprotein B-containing lipoproteins in adult Japanese patients with HoFH.

Topics & Keywords

Lipoproteins and Cardiovascular Health Cholesterol and Lipid Metabolism Diabetes, Cardiovascular Risks, and Lipoproteins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Atherosclerosis and Thrombosis

Volume 24, Issue 4, pp. 402-411

DOI: 10.5551/jat.38216

Field-Weighted Citation Impact: 5.46