Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein

2017506 citationsJournal Articlegold Open Access

Authors

Yulei Chen · Qingdao National Laboratory for Marine Science and Technology

Siyuan Zhang · Qingdao National Laboratory for Marine Science and Technology

Qizhi Wang · First Affiliated Hospital of Bengbu Medical College

Abstract

Our study revealed a novel aspect of macrophages with respect to cancer metastasis and showed that CHI3L1 could be a marker of metastatic gastric and breast cancer in patients.

Topics & Keywords

Immune cells in cancer Macrophage Migration Inhibitory Factor Histone Deacetylase Inhibitors Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Hematology & Oncology

Volume 10, Issue 1, pp. 36-36

DOI: 10.1186/s13045-017-0408-0

Field-Weighted Citation Impact: 10.40