Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy

2017457 citationsJournal Articlebronze Open Access

Authors

Brian M. Casey · The University of Texas Southwestern Medical Center

Elizabeth Thom · George Washington University

Alan M. Peaceman · Northwestern University

Michael W. Varner · The University of Texas Southwestern Medical Center

Yoram Sorokin · Wayne State University

Deborah G. Hirtz · The University of Texas Southwestern Medical Center

Uma M. Reddy

Abstract

Treatment for subclinical hypothyroidism or hypothyroxinemia beginning between 8 and 20 weeks of gestation did not result in significantly better cognitive outcomes in children through 5 years of age than no treatment for those conditions. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke; ClinicalTrials.gov number, NCT00388297 .).

Topics & Keywords

Thyroid Disorders and Treatments Thyroid Cancer Diagnosis and Treatment Growth Hormone and Insulin-like Growth Factors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 376, Issue 9, pp. 815-825

DOI: 10.1056/nejmoa1606205

Field-Weighted Citation Impact: 37.55