Heavy-quark production in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>p</mml:mi></mml:math>+<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>p</mml:mi></mml:math>and energy loss and flow of heavy quarks in Au + Au collisions at<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>N</mml:mi><mml:mi>N</mml:mi></mml:mrow></mml:msub></mml:msqrt><mml:mo>=</mml:mo><mml:mn>200</mml:mn></mml:mrow></mml:math>GeV

Transverse momentum spectra of electrons (${p}_{T}^{e}$) from semileptonic weak decays of heavy-flavor mesons in the range of $0.3&lt;{p}_{T}^{e}&lt;9.0$ GeV/$c$ have been measured at midrapidity ($|y|&lt;0.35$) by the PHENIX experiment at the Relativistic Heavy Ion Collider in $p+p$ and $\mathrm{Au}+\mathrm{Au}$ collisions at $\sqrt{{s}_{\mathrm{NN}}}=200$ GeV. In addition, the azimuthal anisotropy parameter ${v}_{2}$ has been measured for $0.3&lt;{p}_{T}^{e}&lt;5.0$ GeV/$c$ in $\mathrm{Au}+\mathrm{Au}$ collisions. The substantial modification in the ${p}_{T}^{e}$ spectra in $\mathrm{Au}+\mathrm{Au}$ compared with $p+p$ collisions as well as the nonzero ${v}_{2}$ indicate substantial interactions and flow of heavy quarks in traversing the produced medium. Comparisons of these observables with detailed theoretical calculations can be used to identify the nature of these interactions and to quantify their extent.