A novel adjustable automated system for inducing chronic intermittent hypoxia in mice

20177 citationsJournal Articlegold Open Access

Authors

Dora Polšek · University of Zagreb

Marcel Bago · Semmelweis University

Marija Živaljić · University of Zagreb

Ivana Rosenzweig · King's College London

Zsombor Lacza · Semmelweis University

Srečko Gajović · University of Zagreb

Abstract

The new design of a hypoxic chamber provides a fast, adjustable and reliable model of obstructive sleep apnea, which was validated by apoptosis of hippocampal neurons.

Topics & Keywords

Sleep and Wakefulness Research Obstructive Sleep Apnea Research Neuroscience of respiration and sleep

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 12, Issue 3, pp. e0174896-e0174896

DOI: 10.1371/journal.pone.0174896

Field-Weighted Citation Impact: 0.53