Joint ESPGHAN/NASPGHAN Guidelines for the Management of <i>Helicobacter pylori</i> in Children and Adolescents (Update 2016)

The primary goal of clinical investigation is to identify the cause of upper gastrointestinal symptoms rather than H pylori infection. Therefore, we recommend against a test and treat strategy. Decreasing eradication rates with previously recommended treatments call for changes to first-line therapies and broader availability of culture or molecular-based testing to tailor treatment to the individual child.