Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer

2017621 citationsJournal Articlehybrid Open Access

Authors

Fergus J. Couch · Mayo Clinic

Hermela Shimelis · Mayo Clinic

Chunling Hu · Mayo Clinic

Steven N. Hart · Mayo Clinic in Florida

Eric C. Polley · Mayo Clinic in Florida

Jie Na · Mayo Clinic in Florida

Emily Hallberg · Mayo Clinic in Florida

Abstract

This study establishes several panel genes as high- and moderate-risk breast cancer genes and provides estimates of breast cancer risk associated with pathogenic variants in these genes among individuals qualifying for clinical genetic testing.

Topics & Keywords

BRCA gene mutations in cancer Genetic factors in colorectal cancer Genomics and Rare Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Oncology

Volume 3, Issue 9, pp. 1190-1190

DOI: 10.1001/jamaoncol.2017.0424

Field-Weighted Citation Impact: 64.52