Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas

2017300 citationsJournal Articlebronze Open Access

Authors

Sophie Weil · Heidelberg University

Matthias Osswald · University Medical Centre Mannheim

Gergely Solecki · Heidelberg University

Julia Grosch · German Cancer Research Center

Erik Jung · National Center for Tumor Diseases

Dieter Lemke · University Medical Centre Mannheim

Miriam Ratliff

Abstract

TMs can contribute to the resistance against standard treatment modalities in gliomas. Specific inhibition of TMs is a promising approach to reduce local recurrence after surgery and lower resistance to chemotherapy.

Topics & Keywords

Glioma Diagnosis and Treatment Brain Metastases and Treatment Nanoplatforms for cancer theranostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neuro-Oncology

Volume 19, Issue 10, pp. 1316-1326

DOI: 10.1093/neuonc/nox070

Field-Weighted Citation Impact: 13.41