Effect of Hypericum perforatum (St John's Wort) in Major Depressive Disorder

2002479 citationsJournal Article

Authors

Abstract

This study fails to support the efficacy of H perforatum in moderately severe major depression. The result may be due to low assay sensitivity of the trial, but the complete absence of trends suggestive of efficacy for H perforatum is noteworthy.

Topics & Keywords

Natural Compound Pharmacology Studies Medicinal Plant Extracts Effects Tryptophan and brain disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 287, Issue 14, pp. 1807-1807

DOI: 10.1001/jama.287.14.1807

Field-Weighted Citation Impact: 76.86