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This study assesses the 2002 world health organisation Active Ageing Framework and how it applies to developing countries using data from Zambia. Up to date, there is little or no evidence of studies conducted to answer whether or not the 2002 world health organisation Active Ageing Framework is applicable to developing countries like Zambia. This study set out to (1) explore which of the determinants of the active ageing framework apply to Africa and Zambia in particular and, (2) the influence of HIV/AIDS on active ageing in general. A non-experimental exploratory research design was used to collect data for this paper. Snowball and purposive sampling was employed to select 690 respondents (284 males and 406 females) for the study. The study reveals that income accessibility (Economic Determinant), functional limitations (Health Determinants), low self-esteem and loneliness (Personal/Behavioural Determinants), low family and peer interactions (Social Determinants) and HIV/AIDS apply to Zambia in determining active ageing. The study suggests that focused research is needed to clarify and specify the role of each determinant, as well as the interactions between determinants in the active ageing process. In fact, the framework proposes that for such studies, a life course approach is required so as to take advantage of transitions and “window of opportunity” for enhancing health, participation and security at different stages. The study also recommends that policies on ageing should be structured to incorporate the applicability of the 2002 world health organisation active ageing framework’s main determinants of active ageing to reflect the Zambian context.